MECHANISM OF ACTION
Tesamorelin is a synthetic version of the brain signal (GHRH, growth hormone releasing hormone) that tells the pituitary gland to release growth hormone. A small chemical modification was made to stop it breaking down too quickly. Like CJC-1295, it stimulates the pituitary to release growth hormone in natural pulses. Unlike CJC-1295, it has a much shorter active period in the body, roughly 30 to 40 minutes. It is one of the very few GHRH-type peptides to have been through full formal regulatory review, which is why so much published data exists on how it behaves. More recent research is also exploring its effects on brain health and memory.
RESEARCH APPLICATIONS
- Growth hormone secretagogue pathway research
- Pulsatile GH release modelling
- IGF-1 signalling studies
- Body-composition research models
- Comparative GHRH-analogue pharmacology
RESEARCH HIGHLIGHTS
Well characterised GHRH analogue
2019One of the more heavily studied growth-hormone-releasing analogues in the literature, used as a reference molecule in pituitary signalling research. Research observations only - not a statement about this product.
Ref: Reviewed in Endocrine Reviews
Pituitary pathway specificity
2007Laboratory work describes it acting on GHRH receptors in the pituitary rather than bypassing them, which is why researchers use it to study natural release patterns.
Ref: Falutz et al.
RESEARCH PROTOCOL NOTES
Chemical Identity
Storage & Stability
Lyophilised: 2–8°C; do not freeze. Reconstituted: use within 3 hours (no preservative in approved formulation). Research multi-dose vials: 2–8°C, 28 days.
Regulatory Status
Unscheduled in South Africa. Supplied for laboratory and research use only. Not a registered medicine, not evaluated by SAHPRA, not for human consumption. WADA prohibited (S2).
Important - read before proceeding
This page is a summary of published scientific literature about a molecule. It is provided for research and educational purposes only. Nothing on this page is medical advice, a diagnosis, a recommendation, a prescription, or a claim that this compound treats, cures, prevents or improves any condition in humans. Research findings described here are observations reported by third-party researchers about the molecule - they are not statements about the product supplied by Bio Intelligence, and they should not be read as an expected outcome.
Compounds supplied are not registered medicines, have not been evaluated by SAHPRA, and are not for human consumption. No dosing, route of administration or usage guidance is provided by Bio Intelligence. If you have a health concern, speak to a registered healthcare practitioner.