Research Compendium/AOD-9604
Weight ManagementResearch OnlyNot For Human Consumption

AOD-9604

GH Fragment 177-191 · Fat Away peptide

A small fragment of the growth hormone molecule. Researchers study it because the fragment behaves differently from the full hormone.

MECHANISM OF ACTION

AOD-9604 is a small piece snipped from the end of human growth hormone. Researchers at Monash University discovered that this specific fragment carries the fat-burning signal but not the growth signal. It works by switching on the fat-breakdown process (called lipolysis) inside fat cells. Crucially, it does not raise IGF-1 (a growth factor that builds muscle) or mess with blood sugar levels, two side effects associated with full growth hormone. It progressed through several rounds of formal clinical study before the research programme was wound down.

RESEARCH APPLICATIONS

  • Adipose tissue metabolism research
  • Beta-3 adrenergic pathway studies
  • GH-fragment comparative pharmacology
  • Metabolic signalling research models

RESEARCH HIGHLIGHTS

Fragment behaves unlike whole GH

2001

Laboratory work reports the fragment acting on lipolytic pathways without the IGF-1 signalling associated with full growth hormone - the main reason it is studied separately. Research observations only.

Ref: Heffernan et al., Endocrinology

RESEARCH PROTOCOL NOTES

Stack contextFound in "Shredded" stack with MOTS-C + Tesamorelin
Physical formSupplied lyophilised (freeze-dried powder) unless stated otherwise
ReconstitutionBacteriostatic water; swirl gently, do not shake

Chemical Identity

Molecular FormulaC78H123N23O23S2
Molecular Weight1817.1 g/mol
CAS Number221231-10-3
SolubilitySoluble in water; bacteriostatic water preferred

Sequence

Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe

Storage & Stability

Lyophilised: 2–8°C or -20°C. Reconstituted: 2–8°C, 28 days. More stable than many larger GH-related peptides.

Regulatory Status

Unscheduled in South Africa. Supplied for laboratory and research use only. Not a registered medicine, not evaluated by SAHPRA, not for human consumption. Not explicitly listed on the WADA prohibited list.

Important - read before proceeding

This page is a summary of published scientific literature about a molecule. It is provided for research and educational purposes only. Nothing on this page is medical advice, a diagnosis, a recommendation, a prescription, or a claim that this compound treats, cures, prevents or improves any condition in humans. Research findings described here are observations reported by third-party researchers about the molecule - they are not statements about the product supplied by Bio Intelligence, and they should not be read as an expected outcome.

Compounds supplied are not registered medicines, have not been evaluated by SAHPRA, and are not for human consumption. No dosing, route of administration or usage guidance is provided by Bio Intelligence. If you have a health concern, speak to a registered healthcare practitioner.

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