MECHANISM OF ACTION
5-Amino-1MQ is not a peptide, it's a small molecule that blocks a specific enzyme called NNMT (nicotinamide N-methyltransferase). This enzyme is very active in fat tissue and plays a role in making fat cells larger and more numerous. When you block it, fat cells shrink and the body produces more NAD+ (a key energy-carrying molecule used by every cell). NAD+ is important for energy production, DNA repair, and ageing, raising it has been a major focus of longevity research. The same enzyme is also found in brain areas that handle dopamine, which is why 5-Amino-1MQ is also studied for cognitive applications.
RESEARCH APPLICATIONS
- NNMT enzyme inhibition research
- NAD⁺ pathway studies
- Adipocyte metabolism research models
- Methylation pathway characterisation
RESEARCH HIGHLIGHTS
NNMT inhibition
2019Research describes selective inhibition of the NNMT enzyme and a downstream rise in cellular NAD⁺, which is the mechanism of interest. Research observations only.
Ref: Neelakantan et al., JACS
RESEARCH PROTOCOL NOTES
Chemical Identity
Storage & Stability
Store at 2–8°C. Small molecule - more stable than peptides. Protect from moisture and light.
Regulatory Status
Unscheduled in South Africa. Supplied for laboratory and research use only. Not a registered medicine, not evaluated by SAHPRA, not for human consumption. Not on the WADA prohibited list.
Important - read before proceeding
This page is a summary of published scientific literature about a molecule. It is provided for research and educational purposes only. Nothing on this page is medical advice, a diagnosis, a recommendation, a prescription, or a claim that this compound treats, cures, prevents or improves any condition in humans. Research findings described here are observations reported by third-party researchers about the molecule - they are not statements about the product supplied by Bio Intelligence, and they should not be read as an expected outcome.
Compounds supplied are not registered medicines, have not been evaluated by SAHPRA, and are not for human consumption. No dosing, route of administration or usage guidance is provided by Bio Intelligence. If you have a health concern, speak to a registered healthcare practitioner.